Michael B. Chavez
I am currently a D3 student at the University of Iowa, College of Dentistry, and a concurrent PhD student in the College of Dentistry at Ohio State University, studying the molecular mechanisms that control mineralization with an emphasis on oral tissues.
My long-term goal is to bridge the knowledge gained in the lab to the patients to improve outcomes and quality of life for patients suffering from mineralized tissue diseases, syndromes, and injuries as an academic clinician scientist.
FEATURED ARTICLES
Loss of Discoidin Domain Receptor 1 Predisposes Mice to Periodontal Breakdown
October 2019, Journal of Dental Research
Authors:
Chavez MB, Kolli TN, Tan MH, Zachariadou C, Wang C, Embree MC, Lira Dos Santos EJ, Nociti FH Jr, Wang Y, Tatakis DN, Agarwal G, Foster BL.
​
Synopsis:
Mice lacking Discoidin Domain Receptor 1 (DDR1) although developed a healthy periodontium into early adulthood spontaneously developed bacterial associated inflammatory bone loss consistent with periodontitis in mid to latter adulthood.
Dentoalveolar Defects in the Hyp Mouse Model of X-linked Hypophosphatemia.
January 2020, Journal of Dental Research
Authors:
Zhang H, Chavez MB, Kolli TN, Tan MH, Fong H, Chu EY, Li Y, Ren X, Watanabe K, Kim DG, Foster BL.
​
Synopsis:
Hyp mice are an established model for XLH. This study examined in detail the dentoalvolar defects in Hyp mice and used high reslolution micro-CT and nanoindentation to examine the perilacular densities of cementocytes, leading the way for future studies to examine how treatments effect these defects.
Authors:
Zhang H, Chavez MB, Kolli TN, Tan MH, Fong H, Chu EY, Li Y, Ren X, Watanabe K, Kim DG, Foster BL.
​
Synopsis:
Hyp mice are an established model for XLH. This study examined in detail the dentoalvolar defects in Hyp mice and used high reslolution micro-CT and nanoindentation to examine the perilacular densities of cementocytes, leading the way for future studies to examine how treatments effect these defects.